BF3 center dot OEt2-Catalyzed Aldol Condensation of Steroid Sapogenins and 2-Oxoacids: A Single Step Conversion of Steroid Spiroketals into Branched alpha,beta-Unsaturated Spirolactones
Por:
Hernandez-Martinez, Juan E., Iglesias-Arteaga, Martin A.
Publicada:
4 ago 2020
Resumen:
BF3OEt2-catalyzed aldol reaction of steroid sapogenins with glyoxylic
acid or pyruvic acid led to compounds in which the novel spirocyclic
side chain bears an alpha,beta-unsaturated lactone. The structures of
the new spirolactones were established with the aid of combined 1D and
2D NMR techniques. A plausible mechanism is described.
Filiaciones:
Hernandez-Martinez, Juan E.:
Univ Nacl Autonoma Mexico, Fac Quim, Mexico City 04510, DF, Mexico
Iglesias-Arteaga, Martin A.:
Univ Nacl Autonoma Mexico, Fac Quim, Mexico City 04510, DF, Mexico
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