Corytophanids Replaced the Pleurodont XY System with a New Pair of XY Chromosomes
Por:
Acosta, Armando, Suarez-Varon, Gabriel, Rodriguez-Miranda, Luis A., Lira-Noriega, Andres, Aguilar-Gomez, Diana, Gutierrez-Mariscal, Mariana, Hernandez-Gallegos, Oswaldo, Mendez-de-la-Cruz, Fausto, Cortez, Diego
Publicada:
1 ene 2019
Resumen:
Almost all lizard families in the pleurodont clade share the same XY system. This system was meticulously studied in Anolis carolinensis, where it shows a highly degenerated Y chromosome and a male-specific X chromosome dosage compensation mechanism. Corytophanids (casque-headed lizards) have been proposed as the only family in the pleurodont clade to lack the XY system. In this study, we worked with extensive genomic and transcriptomic data from Basiliscus vittatus, a member of the Corytophanidae family that inhabits the tropical rainforests of Mexico. We confirmed that B. vittatus underwent a sex chromosome system turnover, which consisted in the loss of the pleurodont XY system and the gain of a new pair of XY chromosomes that are orthologous to chicken chromosome 17. We estimated the origin of the sex chromosome system to have occurred ~63 Ma in the ancestor of corytophanids. Moreover, we identified 12 XY gametologues with particular attributes, such as functions related to the membrane and intracellular trafficking, very low expression levels, blood specificity, and incomplete dosage compensation in males. © The Author(s) 2019. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.
Filiaciones:
Acosta, Armando:
Center for Genome Sciences, UNAM, Cuernavaca, Mexico
UNAM, Ctr Genome Sci, Cuernavaca, Morelos, Mexico
Suarez-Varon, Gabriel:
Laboratorio de Herpetología, Universidad Autónoma del Estado de México, Facultad de Ciencias, Toluca, Mexico
Univ Autonoma Estado Mexico, Fac Ciencias, Lab Herpetol, Toluca, Mexico
Rodriguez-Miranda, Luis A.:
Biology Institute, UNAMMexico City, Mexico
Univ Nacl Autonoma Mexico, Biol Inst, Mexico City, DF, Mexico
Lira-Noriega, Andres:
CONACYT Research Fellow, Red de Estudios Moleculares Avanzados, Instituto de Ecología, Mexico
Inst Ecol, Red Estudios Mol Avanzados, Xalapa, Veracruz, Mexico
Aguilar-Gomez, Diana:
Center for Genome Sciences, UNAM, Cuernavaca, Mexico
UNAM, Ctr Genome Sci, Cuernavaca, Morelos, Mexico
Gutierrez-Mariscal, Mariana:
Biotechnology Institute, UNAM, Cuernavaca, Mexico
UNAM, Biotechnol Inst, Cuernavaca, Morelos, Mexico
Hernandez-Gallegos, Oswaldo:
Laboratorio de Herpetología, Universidad Autónoma del Estado de México, Facultad de Ciencias, Toluca, Mexico
Univ Autonoma Estado Mexico, Fac Ciencias, Lab Herpetol, Toluca, Mexico
Mendez-de-la-Cruz, Fausto:
Biology Institute, UNAMMexico City, Mexico
Univ Nacl Autonoma Mexico, Biol Inst, Mexico City, DF, Mexico
Cortez, Diego:
Center for Genome Sciences, UNAM, Cuernavaca, Mexico
UNAM, Ctr Genome Sci, Cuernavaca, Morelos, Mexico
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