Meduloblastoma en pediatría. Pronóstico y tratamiento en la actualidad
Por:
Rivera-Luna R., Niembro-Zúñiga A.M., Zarco A., Marhx-Bracho A., Cárdenas-Cardós R., Olaya-Vargas A., Rueda-Franco F., Martínez-Ávalos A.
Publicada:
1 ene 2007
Categoría:
Medicine (miscellaneous)
Resumen:
In Mexico, Central Nervous System (CNS) tumors are the third most common childhood cancers. Medulloblastoma constitutes 20% of the primary CNS tumors and 40% of all cerebellar tumors, the single most common brain tumor among children. It originates over the external granular layer that normally migrates from the vermis to the surface of the cerebellum hemispheres and from there to the deep portions of the internal granular layer. These tumors infiltrate profusely the cerebellar cortex. The dissemination process can occur through the spinal fluid with seeding along the subarachnoidal space and around the spinal chord. They eventually produce metastasis mainly to bone, liver, and bone marrow. There is a group of well identified prognostic factors that are relevant for each individual patient and that can be applied for multidisciplinary treatment purposes. The objective of the present review is to emphasize on new research findings and the overall survival that can be achieved with modern treatment programs.
Filiaciones:
Rivera-Luna R.:
Subdireccion de Hematooncología Pediátrica, Instituto Nacional de Pediatría, SSA, México D.F., Mexico
Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, 04530 México, D. F., Mexico
Niembro-Zúñiga A.M.:
Servicio de Oncología, Instituto Nacional de Pediatría, SSA, México D.F., Mexico
Zarco A.:
Servicio de Radioterapia, Instituto Nacional de Pediatría, SSA, México D.F., Mexico
Marhx-Bracho A.:
Servicio de Neurocirugía, Instituto Nacional de Pediatría, SSA, México D.F., Mexico
Cárdenas-Cardós R.:
Servicio de Oncología, Instituto Nacional de Pediatría, SSA, México D.F., Mexico
Olaya-Vargas A.:
Servicio de Oncología, Instituto Nacional de Pediatría, SSA, México D.F., Mexico
Rueda-Franco F.:
Subdireccion de Neurociencias, Instituto Nacional de Pediatría, SSA, México D.F., Mexico
Martínez-Ávalos A.:
Servicio de Quimioterapia Ambulatoria, Instituto Nacional de Pediatría, SSA, México D.F., Mexico
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