Pulmonary embolism and megaloblastic anemia: is there a link? A case report an literature review


Por: Raymundo-Martínez G.I., Gopar-Nieto R., Carazo-Vargas G., Araiza-Garaygordobil D., Scuri S.R., Rodríguez-Chavez L.L., Espinola-Zavaleta N.

Publicada: 1 ene 2018
Categoría: Radiology, nuclear medicine and imaging

Resumen:
Many factors have been associated with venous thromboembolism. Among them, vitamin B12 deficiency can produce elevated homocysteine levels, which is a risk factor for venous embolism, since the latter interferes with the activation of Va coagulation factor by activation of C protein. We present a case of a patient with metabolic syndrome with apparently unprovoked pulmonary embolism. After careful evaluation, megaloblastic anemia was detected. Even though the patient had biochemistry findings of hemolysis and blood smear did not showed fragmented erythrocytes, which is consistent with pseudo-microangiopathic hemolytic anemia. © 2018 The Authors

Filiaciones:
Raymundo-Martínez G.I.:
 Fellows in training of Cardiology, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico

Gopar-Nieto R.:
 Fellows in training of Cardiology, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico

Carazo-Vargas G.:
 Fellows in training of Cardiology, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico

Araiza-Garaygordobil D.:
 Chief of Fellowship in Cardiology and fellow in Coronary Care Unit, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico

Scuri S.R.:
 Chief of Fellowship in Cardiology, Italian Hospital, La Plata, Buenos Aires, Argentina

Rodríguez-Chavez L.L.:
 Out-patient Clinic, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico

Espinola-Zavaleta N.:
 Nuclear Cardiology, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico
ISSN: 19300433
Editorial
Elsevier Inc, Estados Unidos America
Tipo de documento: Article
Volumen: 13 Número: 6
Páginas: 1212-1215

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