Asma y reflujo gastroesofágico. Correlación diagnóstica entre gamagrafía y endoscopía digestiva.


Por: Soria González J.E., Gómez Vera J., Cruz Parada M.C., Flores Sandoval G., Orea Solano M.

Publicada: 1 ene 2001
Resumen:
AIMS: Incidence of gastroesophageal reflux (RGE) in asthmatic it is considered be of the rang of 33% until 89%. RGE can be classic or atypical and 30% will be payees of silent reflux. It considers at the moment so much as standard of gold to 24 hours pH esophagus like endoscopic digestive and biopsy, being determined a smaller sensibility to gastric gammagraphic but maybe a bigger utility in relation to their readiness and access easiness. OBJECTIVE: Comparative study is presented that reports sensibility/specificity of gastric gammagraphic, relating it with digestive endoscopic study and biopsy report. METHOD: All asthmatic patient of difficult control and of up to 6 years, selected of the External Consultation of the Service. Gastric gammagraphic was determined and later on the panendoscopic study with taking of biopsy. It integrated sensibility specificity for gammagraphic gastric. RESULTS: Study that understood 8 months, with a total of 44 patients, with a range of 1.4 year-old age to 6 years. Gastric gammagram was reported positive in 25 patients, (56.8%) and negative in 19,(43.18%). Endoscopic studies demonstrated incompetent hiatus in 33 (75%), esophagitis of variable degree in 20 patients, (45.4%), Gastritis in 8 (18.1%) and normal study in 8, (18.1%). Histopathologies: Esophagitis of variable degree in 33 patients (75%), chronic gastritis in 2 patients, (4.5%), Esophagus of Barrett in 2 patients, (4.5%), and normal histopathologic study in 7,(15.9%). Of the 44 patients, 81.5% showed significant reflux. It is integrated a sensibility and specificity of the gastric gammagraphic of 71.4% and 54.2%, respectively. CONCLUSIONS: Gastric gammagraphic contributes sensibility it mediates but acceptable for diagnose of RGE. In asthmatic of difficult control, it should be considered initially endoscopic study. The probability of RGE should always take into account in all asthmatic patient.

Filiaciones:
Soria González J.E.:
 R-V alergia e inmunología clínica, Hospital Regional Lic. Adolfo López Mateos, Instituto de Seguridad Social al Servicio de los Trabajadores del Estado (ISSSTE), México, DF

Gómez Vera J.:
 R-V alergia e inmunología clínica, Hospital Regional Lic. Adolfo López Mateos, Instituto de Seguridad Social al Servicio de los Trabajadores del Estado (ISSSTE), México, DF

Cruz Parada M.C.:
 R-V alergia e inmunología clínica, Hospital Regional Lic. Adolfo López Mateos, Instituto de Seguridad Social al Servicio de los Trabajadores del Estado (ISSSTE), México, DF

Flores Sandoval G.:
 R-V alergia e inmunología clínica, Hospital Regional Lic. Adolfo López Mateos, Instituto de Seguridad Social al Servicio de los Trabajadores del Estado (ISSSTE), México, DF

Orea Solano M.:
 R-V alergia e inmunología clínica, Hospital Regional Lic. Adolfo López Mateos, Instituto de Seguridad Social al Servicio de los Trabajadores del Estado (ISSSTE), México, DF
ISSN: 0000360P
Tipo de documento: Article
Volumen: 48 Número: 2
Páginas: 48-55
ID de PubMed: 11421175