Virus del papiloma humano. Desde su descubrimiento hasta el desarrollo de una vacuna. Parte I/III
Por:
Ochoa-Carrillo F.J.
Publicada:
1 ene 2014
Resumen:
One of the greatest achievements of medicine is the understanding of the infection from human papillomavirus (HPV) and its causal relation to some types of cancer. Most people with HIV infections have no symptoms, so it may go unnoticed and the infection is limited by the host. It is important to note that less than 10% of patients have a persistent infection, which can lead to the development of malignancy. HPV requires a small tissue damage placed in a transitional area of epithelia, such as the existent in the cervix, anus or tonsils, to infect cells. The genotypes of HPV that affect the mucous membranes are sexually transmitted and are classified as low and high risk. The high-risk genotypes are associated with cervical cancer, vulvar, vaginal, penile, anal and oropharyngeal tumors. It is accepted that up to 25% of sexually active people are infected with genital HPV and more than 50% will be infected at least once during their lifetime. An essential part of managing HPV infections is prevention so that vaccines represent a valuable tool. The quadrivalent vaccine against human papillomavirus is available since 2006 and the literature considers it as a very important implement, due to the degree of protection provided against genital warts and cervical cancer. © 2014 Gaceta Mexicana de Oncología.
Filiaciones:
Ochoa-Carrillo F.J.:
Especialidad en Cirugía Oncológica, Instituto Nacional de Cancerología, Av. San Fernando N° 22, Colonia Sección XVI,México D.F., Mexico
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