Cáncer de piel no melanoma manejado con braquiterapia superficial de alta tasa de dosis comparando molde y Leipzig
Por:
Villavicencio-Queijeiro M.A., Bautista-Hernández M.Y., Monterrubio M.-J.J., Ruesga-Vásquez D., Luján-Castilla P.J., Fuentes-Mariles S.G., Márquez-Santana T.G., Salinas-Gonzáles J.S.
Publicada:
1 ene 2011
Resumen:
Introduction: Non melanoma skin cancer is one of five causes of dead in men and women in reproductive age in Mexico. Objective: To compare the local control in CPNM with superficial brachytherapy (BQT) of high dose rate (HDR) with Leipzig or mold. Methods: Retrospective research in 70 patients with CPNM in head and neck area, treated only with BQT, superficial HDR, in the BQT Department of the Radiotherapy Service in Hospital General de Mexico from April 1st 2005 to December 31st, 2009. Patients were divided into 5 non-homogenous groups (nose, eye, face, hand and ear). On one group, three of the patients had more than two injuries, so two mold and Leipzig applicators were used to treat them; the patients were analyzed on a separate group. In all the cases the prescribed dose was 5064 cGy in 12 fractions, 3 times a week (Monday, Wednesday and Friday) for 4 weeks. In the applicator's choice the type of surface was essential. In homogenous surfaces Leipzig applicators were used while in the inhomogeneous surface the mold applicator was chosen to guarantee the dose prescription. Results: It was found that in the 5 groups the local control is similar with the 2 types of applicators, except for the external ear canal in which the local failure is presented in up to 20%. Conclusion: In CPNM head and neck area local control is up to 95% with the superficial brachytherapy (BQT) use of high doses rate (HDR). The surface type must be taken into account in the applicators choice (Leipzig or mould). The late toxicity percentage (hyperpigmentation) was 21.4% with Leipzeig and 40% with mould.
Filiaciones:
Villavicencio-Queijeiro M.A.:
Departamento de Braquiterapia, Hospital General de México, Mexico
Hospital General de México, Mexico
Bautista-Hernández M.Y.:
Departamento de Braquiterapia, Hospital General de México, Mexico
Hospital General de México, Mexico
Monterrubio M.-J.J.:
Departamento de Braquiterapia, Hospital General de México, Mexico
Hospital General de México, Mexico
Ruesga-Vásquez D.:
Departamento de Braquiterapia, Hospital General de México, Mexico
Hospital General de México, Mexico
Luján-Castilla P.J.:
Hospital General de México, Mexico
Fuentes-Mariles S.G.:
Hospital General de México, Mexico
Márquez-Santana T.G.:
Hospital General de México, Mexico
Salinas-Gonzáles J.S.:
Hospital General de México, Mexico
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