Genome Wide Computational Identification of Tuna (Thunnus orientalis) MicroRNAs and Their Targets
Por:
Paul, Sangita Chowdhury, Sharma, Ashutosh, Mehta, Richa, Paul, Sujay
Publicada:
1 dic 2018
Ahead of Print:
1 ene 2018
Categoría:
Oceanography
Resumen:
Applying genome-wide computational-based approaches (using the draft
genome sequence published in recent years) and following a set of strict
filtering criteria, a total of 48 potentially conserved microRNAs
belonging to 30 families were identified from economically important
fish tuna (Thunnus orientalis). Using BLAST and RNA hybrid program a
total of 19 potential miRNA targets were also identified in this study,
which includes a number of signaling molecules (serine/threonine-protein
kinase, GTPase activating protein etc.) and transcription factors (F-box
protein, zinc finger protein etc.). This study provides the basis for
gaining a better understanding of miRNA-mediated gene regulatory
processes in fishes.
Filiaciones:
Paul, Sangita Chowdhury:
Azul Natural S.A. de C.V, Durango, Mexico
Institute of Biotechnology, National Autonomous University of Mexico, Morelos, Mexico
Azul Nat SA de CV, Durango 34190, Mexico
Univ Nacl Autonoma Mexico, Inst Biotechnol, Cuernavaca 62210, Morelos, Mexico
Sharma, Ashutosh:
School of Engineering and Sciences, Monterrey Institute of Technology and Higher Education, Querétaro, Mexico
Monterrey Inst Technol & Higher Educ, Sch Sci & Engn, Queretaro 76130, Mexico
Mehta, Richa:
Biotechnology Research Center (CEIB), Autonomous University of Mexico State, Cuernavaca, Mexico
Autonomous Univ Mexico State, Biotechnol Res Ctr CEIB, Cuernavaca 62209, Morelos, Mexico
Paul, Sujay:
Azul Natural S.A. de C.V, Durango, Mexico
Institute of Biotechnology, National Autonomous University of Mexico, Morelos, Mexico
Azul Nat SA de CV, Durango 34190, Mexico
Bose Inst, Div Plant Biol, Kolkata 700054, India
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