Mitochondrial DNA Analysis of Mazahua and Otomi Indigenous Populations from Estado de Mexico Suggests a Distant Common Ancestry
Por:
Gonzalez-Oliver, Angelica, Garfias-Morales, Ernesto, Smith, David Glenn, Quinto-Sanchez, Mirsha
Publicada:
1 jul 2018
Resumen:
The indigenous Mazahua and Otomi have inhabited the same localities in
Estado de Mexico since pre-Columbian times. Their languages, Mazahua and
Otomi, belong to the Oto-Manguean linguistic family, and although they
share cultural traditions and a regional history that suggest close
genetic relationships and common ancestry, the historical records
concerning their origin are confusing. To understand the biological
relationships between Mazahua and Otomi, we analyzed mitochondrial DNA
(mtDNA) genetic variation. We identified the mtDNA haplogroups by
restriction fragment length polymorphism typing and sequenced
hypervariable region 1 of the mtDNA control region in 141 Mazahua and
100 Otomi. These results showed that Otomi exhibit a higher frequency of
haplogroup A than B, whereas Mazahua exhibit the opposite pattern. In
the Otomi EM population the most frequent subhaplogroups are, in order
of frequency, A2, B2, and C1, whereas in the Mazahua 1 population they
are B2, D1, and A2. The most frequent haplotypes (Ht) of haplogroups A
and B are Ht2 (A) and Ht58 (B2g1) in Mazahua 1 and Ht8 (A2), Ht22
(A2ao1), and Ht53 (B2c2b) in Otomi EM. The genetic diffferences between
the Mazahua 1 and Otomi EM suggest a distant shared ancestry and a
moderate degree of maternal admixture that has not obscured the
diffference of their mtDNA patterns. These unexpected results suggest
the Mazahua and Otomi probably descend from the same group but separated
very early and admixed with other Mesoamerican populations before their
arrival in Central Mexico. The historical evidence of conflicting
relations between the Mazahua and Otomi and the almost nonexistence of
marriage between them could be responsible for maintaining only a
moderate degree of maternal admixture.
Filiaciones:
Gonzalez-Oliver, Angelica:
Univ Nacl Autonoma Mexico, Fac Ciencias, Dept Biol Celular, Mexico City, DF, Mexico
Garfias-Morales, Ernesto:
Univ Nacl Autonoma Mexico, Fac Ciencias, Dept Biol Celular, Mexico City, DF, Mexico
Smith, David Glenn:
Univ Calif Davis, Dept Anthropol, Davis, CA 95616 USA
Quinto-Sanchez, Mirsha:
Univ Nacl Autonoma Mexico, Fac Ciencias, Dept Biol Celular, Mexico City, DF, Mexico
Univ Nacl Autonoma Mexico, Fac Med, Ciencia Forense, Mexico City, DF, Mexico
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