Review: “Pyrophosphate and pyrophosphatases in plants, their involvement in stress responses and their possible relationship to secondary metabolism”
Por:
Gutiérrez-Luna F.M., Hernández-Domínguez E.E., Valencia-Turcotte L.G., Rodríguez-Sotres R.
Publicada:
1 feb 2018
Resumen:
Pyrophosphate (PPi) is produced as byproduct of biosynthesis in the cytoplasm, nucleus, mitochondria and chloroplast, or in the tonoplast and Golgi by membrane-bound H+-pumping pyrophosphatases (PPv). Inorganic pyrophosphatases (E.C. 3.6.1.1; GO:0004427) impulse various biosynthetic reactions by recycling PPi and are essential to living cells. Soluble and membrane-bound enzymes of high specificity have evolved in different protein families and multiple pyrophosphatases are encoded in all plant genomes known to date. The soluble proteins are present in cytoplasm, extracellular space, inside chloroplasts, and perhaps inside mitochondria, nucleus or vacuoles. The cytoplasmic isoforms may compete for PPi with the PPv enzymes and how PPv and soluble activities are controlled is currently unknown, yet the cytoplasmic PPi concentration is high and fairly constant. Manipulation of the PPi metabolism impacts primary metabolism and vice versa, indicating a tight link between PPi levels and carbohydrate metabolism. These enzymes appear to play a role in germination, development and stress adaptive responses. In addition, the transgenic overexpression of PPv has been used to enhance plant tolerance to abiotic stress, but the reasons behind this tolerance are not completely understood. Finally, the relationship of PPi to stress suggest a currently unexplored link between PPi and secondary metabolism. © 2017 Elsevier B.V.
Filiaciones:
Gutiérrez-Luna F.M.:
FACULTAD DE QUÍMICA, UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, Ave. Universidad 3000, Cd. Universitaria, Del. Coyoacán, Mexico City, Mexico
Hernández-Domínguez E.E.:
INSTITUTO DE ECOLOGÍA A.C., Carretera antigua a Coatepec 351, El Haya, Xalapa, Veracruz, Mexico
Valencia-Turcotte L.G.:
FACULTAD DE QUÍMICA, UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, Ave. Universidad 3000, Cd. Universitaria, Del. Coyoacán, Mexico City, Mexico
Rodríguez-Sotres R.:
FACULTAD DE QUÍMICA, UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, Ave. Universidad 3000, Cd. Universitaria, Del. Coyoacán, Mexico City, Mexico
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