Mediators of episodic memory decay across the adult life span


Por: Cansino S., Torres-Trejo F., Estrada-Manilla C., Hernández-Ramos E., Martínez-Galindo J.G., Gómez-Fernández T., Ayala-Hernández M., Ramírez-González M.D., Ruiz-Velasco S.

Publicada: 8 feb 2018
Categoría: Multidisciplinary

Resumen:
The ability to remember the details of our own experiences declines gradually as we get old. The reason for this decay has been attributed to several factors besides age, such as education, nutrient intake and health status. However, the influence of these factors has mainly been examined individually and rarely together. Here we identify those factors that jointly act as mediators of episodic memory decay across the adult life span. We examined source memory in a lifespan sample of 1557 healthy adults. A total of 70 physical, biological and lifestyle variables were measured and introduced into a structural equation model as potential mediators that intervene between age and source memory. Only 14 mediator variables reliably mediated source memory decay; notably, eight of these variables have an effect on the cardiovascular system. The model unequivocally highlights that the mediators that may impair cardiovascular functioning also impact brain resources involved in episodic memory. We identified the factors that are relevant to episodic memory decline when they interact together as occurs in real life. © 2018 The Author(s).

Filiaciones:
Cansino S.:
 Laboratory of NeuroCognition, Faculty of Psychology, National Autonomous University of Mexico, Mexico City, Mexico

Torres-Trejo F.:
 Laboratory of NeuroCognition, Faculty of Psychology, National Autonomous University of Mexico, Mexico City, Mexico

Estrada-Manilla C.:
 Laboratory of NeuroCognition, Faculty of Psychology, National Autonomous University of Mexico, Mexico City, Mexico

Hernández-Ramos E.:
 Laboratory of NeuroCognition, Faculty of Psychology, National Autonomous University of Mexico, Mexico City, Mexico

Martínez-Galindo J.G.:
 Laboratory of NeuroCognition, Faculty of Psychology, National Autonomous University of Mexico, Mexico City, Mexico

Gómez-Fernández T.:
 Laboratory of NeuroCognition, Faculty of Psychology, National Autonomous University of Mexico, Mexico City, Mexico

Ayala-Hernández M.:
 Laboratory of NeuroCognition, Faculty of Psychology, National Autonomous University of Mexico, Mexico City, Mexico

Ramírez-González M.D.:
 Department of Pharmacology, School of Medicine, National Autonomous University of Mexico, Mexico City, Mexico

Ruiz-Velasco S.:
 Applied Mathematics and Systems Research Institute, National Autonomous University of Mexico, Mexico City, Mexico
ISSN: 20452322
Editorial
NATURE PUBLISHING GROUP, MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND, Reino Unido
Tipo de documento: Article
Volumen: 8 Número: 1
Páginas:
WOS Id: 000424448400012
ID de PubMed: 29422554