Cutaneous blastomycosis. An imported case with good response to itraconazole
Por:
Bonifaz, Alexandro, Morales, Diana, Morales, Neredi, Mercadillo, Patricia, Gonzalez, Gloria M., Hernandez-Hernandez, Francisca, Araiza, Javier, Vazquez-Gonzalez, Denisse
Publicada:
31 ene 2016
Resumen:
Background: Blastomycosis is a subacute or chronic deep mycosis caused
by a dimorphic fungus called Blastomyces dermatitidis, which generally
produces a pulmonary form of the disease and, to a lesser extent,
extra-pulmonary forms such as cutaneous, osteoarticular and
genitourinary, among others. Cutaneous blastomycosis is the second
clinical presentation in frequency. It is considered as primary when it
begins by inoculation of the fungus due to traumas, and secondary when
the lung fails to contain the infection.
Case-report: We present the case of a 57 year-old male who had a 5
year-history of an irregularly shaped verrucous infiltrative plaque
related to and insect bite and posterior trauma due to the manipulation
of the lesion. B. dermatitidis was identified using direct examination,
stains, isolation in culture media, histopathology, and molecular
studies. An antifungal susceptibility test was performed using method
M38-A2 (CLSI). Clinical and mycological cure was achieved with
itraconazole.
Conclusions: This cutaneous blastomycosis case acquired in the United
States (Indianapolis) is rather interesting and looks quite similar to
other mycoses such as coccidioidomycosis or sporotrichosis. The
presented case shows one of the multiple issues concerning migration
between neighboring countries. (C) 2014 Revista Iberoamericana de
Micologia. Published by Elsevier Espana, S.L.U. All rights reserved.
Filiaciones:
Bonifaz, Alexandro:
Hosp Gen Mexico City, Serv Dermatol, Mexico City, DF, Mexico
UANL, Fac Med, Dept Microbiol, Monterrey, Mexico
Morales, Diana:
Hosp Gen Mexico City, Serv Dermatol, Mexico City, DF, Mexico
Morales, Neredi:
Hosp Gen Mexico City, Serv Dermatol, Mexico City, DF, Mexico
Mercadillo, Patricia:
Hosp Gen Mexico City, Serv Dermatol, Mexico City, DF, Mexico
Gonzalez, Gloria M.:
UANL, Fac Med, Dept Microbiol, Monterrey, Mexico
Hernandez-Hernandez, Francisca:
Univ Nacl Autonoma Mexico, Fac Med, Dept Microbiol & Parasitol, Lab Micol Med, Mexico City, DF, Mexico
Araiza, Javier:
Hosp Gen Mexico City, Serv Dermatol, Mexico City, DF, Mexico
Vazquez-Gonzalez, Denisse:
Hosp Gen Mexico City, Serv Dermatol, Mexico City, DF, Mexico
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