Organ Damage and Quality of Life in Antiphospholipid Syndrome
Por:
Alba, P., Gomez-Puerta, J. A., Goycochea-Robles, M. V., Amigo, M. C.
Publicada:
1 ene 2016
Categoría:
Rheumatology
Resumen:
Antiphospholipid syndrome (APS) affects young patients in the most
productive years of their life, and the consequences of organic or
tissue damage involve a decrease in health-related quality of life
(HRQoL). While acute disease manifestations of APS are well known,
information on the long-term prognosis and damage in affected patients
is still very limited. Systemic lupus erythematosus (SLE) patients would
be expected to experience long-term complications and even die as a
consequence of APS. Organ damage in APS has been evaluated using
different methods and definitions, including the SLICC/ACR Damage Index
(SDI), which tend to underestimate aPL-related damage. A new damage
index in APS has been proposed (DIAPS), and it seems to be more accurate
than SDI. Given the implications for morbidity and mortality, it is
imperative to assess accurately aPL-related damage and HRQoL in patients
with APS.
Filiaciones:
Alba, P.:
Univ Nacl Cordoba, Hosp Cordoba, Catedra Med 1, UHMI 3, Libertad 2051, RA-5000 Cordoba, Argentina
Gomez-Puerta, J. A.:
Univ Antioquia, Grp Inmunol Celular & Inmunogenet GICIG, Calle 67 53-108, Medellin, Colombia
Goycochea-Robles, M. V.:
Univ Nacl Autonoma Mexico, Hosp Gen Reg 1, IMSS, Unidad Invest Epidemiol Clin, Gabriel Mancera 222, Mexico City 03100, DF, Mexico
Amigo, M. C.:
Univ Nacl Autonoma Mexico, Ctr Med ABC, Sur 136 116, Mexico City 01120, DF, Mexico
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