Penoscopy and urethral cytology in men whose partners had human papillomavirus cervical lesions [Penoscopia y citología uretral en hombres con parejas que presentan lesiones cervicales por virus del papiloma humano]
Por:
Alarcón-Herrera A., Cervantes-Sánchez A., Meneses-Miranda T., Castillejos-López M., Astudillo-De La Vega H., Tena-Suck M.L.
Publicada:
1 ene 2010
Categoría:
Medicine (miscellaneous)
Resumen:
Objective: The aim of this study was to identify human papillomavirus lesions in a group of men whose sexual partners had cervical intraepithelial lesions associated with low-grade HPV confirmed by PCR-DNA. We carried out a correlation between urethral cytology penoscopy data and PCR-DNA results. Methods: We studied 100 male volunteers with an age range of 21-45 (median 30 years) and divided them into two groups according to the identified virus; two groups were conformed, a high risk and a low risk virus. Results: For the penoscopy data we included the following: type of hirsutoide papillomatosis in 40 (40%) cases, common warts in 24 (24%) cases, papillomatosis in plaque in 6 (6%) and 47% displayed an urethra with a foamy appearance. In urethral cytology we did not find evidence of koilocytes in 58% and 42% showed no koilocytes. Inflammation was observed in 44 cases; an added infection was noted among 60 cases. Depending on the type of infection we found: non-specific bacteria in 8%, bacillary in 10%, mixed infection in 12%, changes suggestive of Gardnerella vs 24%, and Chlamydia treatment in 6%. Dyskeratosis was noted in 47% of study participants. 67 patients were treated with imiquimod cream 5% and 33% received non-specific treatment. Regarding improvement we noted that 67 (67%) cases showed 46/67 hypochromic stains after treatment with imiquimod. Disappearance of the lesions in the penis were observed among 65 cases and only 35 remained with lesions. Regarding high-risk HPV we found a significant difference in odor (p =,004, phi = .004), urethral discharge (p = .007), pearly papules in raphe (p = .023), with inflammation, dyskeratosis and added infection (p = .000 respectively). We also noted hypochromic spots or skin discoloration after treatment with imiquimod among 5% of subjects (p = .046). Conclusions: In our study we observed that high-risk HPV is associated with increased penile lesions and frank evidence of koilocytes in urethral cytology. We recommend that sexual partners of women with cervical lesions associated with HPV complete a control study with penoscopy data and urethral cytology, since most have concurrent infections and lesions that can treated in early stages.
Filiaciones:
Alarcón-Herrera A.:
Servicio de Ginecoobstetricia, Secretaría de Salud del Estado de Guerrero, Mexico
Cervantes-Sánchez A.:
Servicio de Urología, Hospital Regional, Instituto de Seguridad Y Servicios Social de Los Trabajadores del Estado, Chilpancingo, Guerrero, Mexico
Meneses-Miranda T.:
Clínica de Displasia, Hospital Regional, Instituto de Seguridad Y Servicios Social de Los Trabajadores del Estado, Chilpancingo, Guerrero, Mexico
Castillejos-López M.:
Investigación en Tuberculosis, Departamento de Epidemiología, Instituto Nacional de Enfermedades Respiratorias, México D.F., Mexico
Astudillo-De La Vega H.:
Hospital de Oncología, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México D.F., Mexico
Tena-Suck M.L.:
Departamento de Neuropatología, Instituto Nacional de Neurología Y Neurocirugía Manuel Velasco Suárez, SSA, México D.F., Mexico
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