Triterpenoids from Hippocratea excelsa. The crystal structure of 29-hydroxytaraxerol
Por:
Aguilar-Gonzalez A.R., Mena-Rejón G.J., Padilla-Montaño N., Toscano A., Quijano L.
Publicada:
1 ene 2005
Resumen:
The root bark of Hippocratea excelsa afforded a new derivative of ?-amyrin, which was identified as its ferulate, together with components new in this species. They were identified as the rare 29-hydroxytaraxerol, 29-hydroxyglutinol, 29-hydroxyfriedelin and the sterol 6?-hydroxystigmast- 4-en-3-one. The known triterpene quinone methides pristimerin and tingenone characteristics of this genus, ?-sitosterol, trans-polyisoprene, squalene, ?-amyrin, and the alditol galacticol characteristic of the Celastraceae were also isolated. The structures were established on the basis of spectral analysis, including homo- and heteronuclear correlation NMR experiments (COSY, DEPT, HMQC and HMBC) and by comparison with data reported in the literature. The structure of 29-hydroxytaraxerol was confirmed by X-ray diffraction. The antimicrobial and antifungal activities of the compounds were studied, but no significant activity was found. © 2005 Verlag der Zeitschrift für Naturforschung.
Filiaciones:
Aguilar-Gonzalez A.R.:
Labratorio de Química Orgánica de Investigación, Facultad de Química, Universidad Autónoma de Yucatán, Calle 41 No. 421, Col. Industrial, Mérida, Yucatán, Mexico
Mena-Rejón G.J.:
Labratorio de Química Orgánica de Investigación, Facultad de Química, Universidad Autónoma de Yucatán, Calle 41 No. 421, Col. Industrial, Mérida, Yucatán, Mexico
Padilla-Montaño N.:
Labratorio de Química Orgánica de Investigación, Facultad de Química, Universidad Autónoma de Yucatán, Calle 41 No. 421, Col. Industrial, Mérida, Yucatán, Mexico
Toscano A.:
Instituto de Química, UNAM, Ciudad Universitaria, Circuito Exterior, 04510, México, D.F., Mexico
Quijano L.:
Instituto de Química, UNAM, Ciudad Universitaria, Circuito Exterior, 04510, México, D.F., Mexico
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