Spectrophotometric determination of Diclofenac sodium with Methylene Blue


Por: Botello J.C., Pérez-Caballero G.

Publicada: 1 ene 1995
Resumen:
A sensitive spectrophotometric method was established for the determination of Diclofenac sodium (DS) with Methylene Blue (MB) as analytical reagent. It was found that DS reacts with an excess of MB in the pH range 9.2-9.4, to form a chloroform-extractable blue ion-association complex. Good agreement with Beer's law was found in the range of DS concentrations of 0.8-6.4 ?g/ml with a detection limit of 0.37 ?g/ml. The method was applied for the determination of DS in various tableted forms with a good precision. © 1994.

Filiaciones:
Botello J.C.:
 Facultad de Estudios Superiores Cuautitlán U.N.A.M., Sección de Química Analítica, Campo Uno. Av. Primero Mayo, s/N Cuautitlan Izcalli, C.P. 54740 Estado de México, Mexico

Pérez-Caballero G.:
 Facultad de Estudios Superiores Cuautitlán U.N.A.M., Sección de Química Analítica, Campo Uno. Av. Primero Mayo, s/N Cuautitlan Izcalli, C.P. 54740 Estado de México, Mexico
ISSN: 00399140
Editorial
ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, Países Bajos
Tipo de documento: Article
Volumen: 42 Número: 1
Páginas: 105-108
WOS Id: A1995QB75400017
ID de PubMed: 18966209