Contrast-enhanced digital mammography and angiogenesis
Por:
Rosado-Méndez I., Palma B.A., Villaseñor Y., Benítez-Bribiesca L., Brandan M.E.
Publicada:
1 ene 2007
Categoría:
Physics and Astronomy (miscellaneous)
Resumen:
Angiogenesis could be a means for pouring contrast media around tumors. In this work, optimization of radiological parameters for contrast-enhanced subtraction techniques in mammography has been performed. A modification of Lemacks' analytical formalism was implemented to model the X-ray absorption in the breast with contrast medium and detection by a digital image receptor. Preliminary results of signal-to-noise ratio analysis show the advantage of subtracting two images taken at different energies, one prior and one posterior to the injection of contrast medium. Preliminary experimental results using a custom-made phantom have shown good agreement with calculations. A proposal is presented for the clinical application of the optimized technique, which aims at finding correlations between angiogenesis indicators and dynamic variables of contrast medium uptake. © 2007 American Institute of Physics.
Filiaciones:
Rosado-Méndez I.:
Instituto de Física, Universidad Nacional Autónoma, Mexico
UN AMMedical Physics program, Mexico City, Mexico
Palma B.A.:
Instituto de Física, Universidad Nacional Autónoma, Mexico
UN AMMedical Physics program, Mexico City, Mexico
Villaseñor Y.:
Instituto Nacional de Cancerología (INCan), Mexico
Benítez-Bribiesca L.:
Centro Médico Nacional Siglo XXI, Mexico
Brandan M.E.:
Instituto de Física, Universidad Nacional Autónoma, Mexico
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