Tyrosinase Inhibitors from Galls of Rhus javanica Leaves and Their Effects on Insects
Por:
Kubo I., Kinst-Hori I., Nihei K.-I., Soria F., Takasaki M., Calderón J.S., Céspedes C.L.
Publicada:
1 ene 2003
Resumen:
As a defense mechanism of the leaves of Rhus javanica (Anacardiaceae) against the aphid Melaphis chinensis (Aphididae) attack, tannic acid is rapidly accumulated and forms galls along the midrib of the leaves resulting in a unique natural medicine Gallae Rhois. Tannic acid was found to inhibit the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by tyrosinase (EC 1.14.18.1) with an IC50 of 22 ?M. The aphid would detoxify the ingested toxic tannic acid to relatively nontoxic gallic acid, whereas the non-adapted pink bollworm Pectinophora gossypiella larvae are sensitive to the ingested tannic acid.
Filiaciones:
Kubo I.:
Dept. Environ. Sci., Plcy. and Mgmt., University of California, Berkeley, CA 94720-3112, United States
Kinst-Hori I.:
Dept. Environ. Sci., Plcy. and Mgmt., University of California, Berkeley, CA 94720-3112, United States
Nihei K.-I.:
Dept. Environ. Sci., Plcy. and Mgmt., University of California, Berkeley, CA 94720-3112, United States
Soria F.:
Dept. Environ. Sci., Plcy. and Mgmt., University of California, Berkeley, CA 94720-3112, United States
Takasaki M.:
Dept. Environ. Sci., Plcy. and Mgmt., University of California, Berkeley, CA 94720-3112, United States
Calderón J.S.:
Departamento de Productos Naturales, Instituto de Quimica, Ciudad Universitaria, Coyoacan, 04510 México, D. F., Mexico
Céspedes C.L.:
Departamento de Productos Naturales, Instituto de Quimica, Ciudad Universitaria, Coyoacan, 04510 México, D. F., Mexico
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