Microwave-assisted one-pot synthesis of 2-(substituted phenyl)-1H- benzimidazole derivatives
Por:
Navarrete-Vázquez G., Moreno-Diaz H., Estrada-Soto S., Torres-Piedra M., León-Rivera I., Tlahuext H., Muñoz-Muñiz O., Torres-Gómez H.
Publicada:
1 ene 2007
Categoría:
Organic Chemistry
Resumen:
A series of 2-(substituted phenyl)-1H-benzimidazole derivatives with various 5-and 6-position substituents (-H, -CH3, -CF3) were synthesized via microwave irradiation using a short synthetic route and Na2S2O5 as oxidant. This simple, fast, and efficient preparation of benzimidazole derivatives has been developed using readily available and inexpensive reagents (aldehydes and 1,2-phenylenediamines) under solvent-free conditions. Copyright © Taylor & Francis Group, LLC.
Filiaciones:
Navarrete-Vázquez G.:
Faculty of Pharmacy, Autonomous University of Morelos State, Cuernavaca, Mexico
Facultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Mor. 62210, Mexico
Moreno-Diaz H.:
Faculty of Pharmacy, Autonomous University of Morelos State, Cuernavaca, Mexico
Estrada-Soto S.:
Faculty of Pharmacy, Autonomous University of Morelos State, Cuernavaca, Mexico
Torres-Piedra M.:
Faculty of Pharmacy, Autonomous University of Morelos State, Cuernavaca, Mexico
León-Rivera I.:
Chemical Research Center, Autonomous University of Morelos State, Cuernavaca, Mexico
Tlahuext H.:
Chemical Research Center, Autonomous University of Morelos State, Cuernavaca, Mexico
Muñoz-Muñiz O.:
Unit for Service and Support in Analytic Resolution, Veracruzana University, Xalapa, Mexico
Torres-Gómez H.:
Faculty of Sciences, Autonomous University of Morelos State, Cuernavaca, Mexico
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