Corpus callosotomy using conformal stereotactic radiosurgery


Por: Celis M.A., Moreno-Jiménez S., Lárraga-Gutiérrez J.M., Alonso-Vanegas M.A., García-Garduño O.A., Martínez-Juárez I.E., Fernández-Gónzalez M.C.

Publicada: 1 ene 2007
Resumen:
Objects: To show the clinical results of a corpus callosotomy (CC) treatment using conformal stereotactic radiosurgery (SRS) on a patient with medically intractable multifocal epilepsy. Materials and methods: A 17-year-old male patient underwent corpus callosotomy conformal SRS using a dedicated linear accelerator (linac) with dynamic arcs technique. The prescribed dose was 36.0 Gy at the periphery of the rostrum, genu, and a half of the body of the corpus callosum (CCA). At 8 months after conformal SRS, the patient developed a significant brain edema and moderate transitory motor deficit, which were controlled with steroids. After 32 months follow-up, there is an improvement of 84% on drop attacks and generalized tonic - clonic seizures. Conclusions: Conformal SRS for corpus callosotomy with a single isocenter reproduce the results reported on literature using Gamma Knife-based SRS. The results show that this technique is safe and demonstrate its efficacy to control seizures. © Springer-Verlag 2007.

Filiaciones:
Celis M.A.:
 Unidad de Radioneurocirugía, Instituto Nacional de Neurología y Neurocirugia, Insurgentes sur 3877, La Fama, 14269 México, D.F., Mexico

Moreno-Jiménez S.:
 Unidad de Radioneurocirugía, Instituto Nacional de Neurología y Neurocirugia, Insurgentes sur 3877, La Fama, 14269 México, D.F., Mexico

Lárraga-Gutiérrez J.M.:
 Unidad de Radioneurocirugía, Instituto Nacional de Neurología y Neurocirugia, Insurgentes sur 3877, La Fama, 14269 México, D.F., Mexico

Alonso-Vanegas M.A.:
 Subdireccion de Neurocirugía, Instituto Nacional de Neurología y Neurocirugía, Insurgentes sur 3877, La Fama, 14269 México, D.F., Mexico

García-Garduño O.A.:
 Laboratorio de Física Médica, Instituto Nacional de Neurología y Neurocirugía, Insurgentes sur 3877, La Fama, 14269 México, D.F., Mexico

Martínez-Juárez I.E.:
 Subdirección Consulta Externa, Instituto Nacional de Neurología y Neurocirugía, Insurgentes sur 3877, La Fama, 14269 México, D.F., Mexico

Fernández-Gónzalez M.C.:
 Departamento de Neurofisiología, Instituto Nacional de Neurología y Neurocirugia, Insurgentes sur 3877, La Fama, 14269 México, D.F., Mexico
ISSN: 02567040
Editorial
Springer-Verlag, 233 SPRING ST, NEW YORK, NY 10013 USA, Estados Unidos America
Tipo de documento: Article
Volumen: 23 Número: 8
Páginas: 917-920
WOS Id: 000248151400020
ID de PubMed: 17450365