Effects of selected synthetic compounds on growth of Mucor rouxii.


Por: Sabanero M., Rojas E., Torres V., Farfán N., Flores A., Contreras R.

Publicada: 1 ene 1995
Resumen:
The in vitro activity of four synthetic compounds was tested on fungal cells from Mucor rouxii. The compounds included phenylenediamine, two phenolamines, and quinone. At the concentrations tested (10(-2)-10(-4)M) the compounds exhibited antifungal activity, with the exception of quinone. On the basis of their effects on spore germination, and development of hyphae, phenylenediamine was the more active. The mechanism of action of the compounds is still unknown, but hyphae show morphological alterations and disturb the distribution of calcofluor in the cell wall. This suggests variations in the genesis of the cell wall.

Filiaciones:
Sabanero M.:
 Instituto de Investigación en Biología Experimental, Facultad de Química, Universidad de Guanajuato, Mexico

Rojas E.:
 Instituto de Investigación en Biología Experimental, Facultad de Química, Universidad de Guanajuato, Mexico

Torres V.:
 Instituto de Investigación en Biología Experimental, Facultad de Química, Universidad de Guanajuato, Mexico

Farfán N.:
 Instituto de Investigación en Biología Experimental, Facultad de Química, Universidad de Guanajuato, Mexico

Flores A.:
 Instituto de Investigación en Biología Experimental, Facultad de Química, Universidad de Guanajuato, Mexico

Contreras R.:
 Instituto de Investigación en Biología Experimental, Facultad de Química, Universidad de Guanajuato, Mexico
ISSN: 00262633
Tipo de documento: Article
Volumen: 82 Número: 332
Páginas: 173-180
WOS Id: A1995RR81900005
ID de PubMed: 7630325