Decrease in number of hippocampal gamma-aminobutyric acid (GABA) immunoreactive cells in the rat kindling model of epilepsy
Por:
Kamphuis W., Wadman W.J., Buijs R.M., da Silva F.H.L.
Publicada:
1 ene 1986
Resumen:
Daily repeated tetanic electrical stimulation (kindling) of hippocampus or other brain structures leads to progressive increase in epileptiform activity. Since kindling may involve changes in the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), the distribution of this amino acid was studied. A significant decrease in number of GABA immunoreactive positive cell bodies in stimulated CA1 region of the rat hippocampus compared to the contralateral side was found. © 1986 Springer-Verlag.
Filiaciones:
Kamphuis W.:
Department of General Zoology, University of Amsterdam, Kruislaan 320, SM Amsterdam, NL-1098, Netherlands
Wadman W.J.:
Department of General Zoology, University of Amsterdam, Kruislaan 320, SM Amsterdam, NL-1098, Netherlands
Buijs R.M.:
Netherlands Institute for Brain Research, Meibergdreef 33, AZ Amsterdam, NL-1105, Netherlands
da Silva F.H.L.:
Department of General Zoology, University of Amsterdam, Kruislaan 320, SM Amsterdam, NL-1098, Netherlands
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