Double diffusion and immunoelectrophoresis in the diagnosis of human cerebral cysticercosis [INMUNO ELECTROFO RESIS Y DOBLE INMUNODIFUSION EN EL DIAGNOSTICO DE LA CISTICERCOSIS CEREBRAL HUMANA]
Por:
Flisser A., Tarrab R., Willms K., Larralde C.
Publicada:
1 ene 1975
Resumen:
The immune reactivity is described of the sera of humans with different probabilities of suffering from cerebral cysticercosis as measured in immunoelectrophoresis and double diffusion against antigenic fractions from the wall, the liquid and the scolex of Cysticercus cellulosae. The proportion of positive sera with any antigenic fraction increased with the likelihood of suffering from cerebral cysticercosis, although some variation was found between antigenic fractions. Scolex and wall antigens showed the maximal discriminatory power between sick and healthy individuals: the probability of a false positive being less than 0.05 and that of a false negative ranging between 0.4 and 0.5. With these estimates, it is concluded that a positive serum in immunoelectrophoresis or double diffusion against scolex or wall antigens practically establishes the diagnosis of cerebral cysticercosis, although this event occurs in only half of the patients afflicted by the disease. The ease of execution of these tests and their discriminatory power between healthy and sick humans justify their establishment among diagnostic tools useful in cerebral cysticercosis.
Filiaciones:
Flisser A.:
Dept. Biol. Molec., Inst. Invest. Biomed., UNAM, Mexico City, Mexico
Tarrab R.:
Dept. Biol. Molec., Inst. Invest. Biomed., UNAM, Mexico City, Mexico
Willms K.:
Dept. Biol. Molec., Inst. Invest. Biomed., UNAM, Mexico City, Mexico
Larralde C.:
Dept. Biol. Molec., Inst. Invest. Biomed., UNAM, Mexico City, Mexico
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