Electrophysiological Representation of Scratching CPG Activity in the Cerebellum
Por:
Martínez-Silva L., Manjarrez E., Gutiérrez-Ospina G., Quevedo J.N.
Publicada:
28 oct 2014
Resumen:
We analyzed the electrical activity of neuronal populations in the
cerebellum and the lumbar spinal cord during fictive scratching in adult
decerebrate cats before and after selective sections of the
Spino-Reticulo Cerebellar Pathway (SRCP) and the Ventral-Spino
Cerebellar Tract (VSCT). During fictive scratching, we found a
conspicuous sinusoidal electrical activity, called Sinusoidal Cerebellar
Potentials (SCPs), in the cerebellar vermis, which exhibited smaller
amplitude in the paravermal and hemisphere cortices. There was also a
significant spino-cerebellar coherence between these SCPs and the lumbar
sinusoidal cord dorsum potentials (SCDPs). However, during spontaneous
activity such spino-cerebellar coherence between spontaneous potentials
recorded in the same regions decreased. We found that the section of the
SRCP and the VSCT did not abolish the amplitude of the SCPs, suggesting
that there are additional pathways conveying information from the spinal
CPG to the cerebellum. This is the first evidence that the sinusoidal
activity associated to the spinal CPG circuitry for scratching has a
broad representation in the cerebellum beyond the sensory representation
from hindlimbs previously described. Furthermore, the SCPs represent the
global electrical activity of the spinal CPG for scratching in the
cerebellar cortex.
Filiaciones:
Martínez-Silva L.:
Departamento de Fisiología, Biofísica y Neurociencias, CINVESTAV, Mexico City, Mexico
Manjarrez E.:
Instituto de Fisiología, BUAP, Puebla, Mexico
Gutiérrez-Ospina G.:
Univ Nacl Autonoma Mexico, Inst Invest Biomed, Mexico City, DF, Mexico
Instituto de Investigaciones Biomédicas - UNAM, México City, Mexico
Quevedo J.N.:
Departamento de Fisiología, Biofísica y Neurociencias, CINVESTAV, Mexico City, Mexico
Gold
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