Racial Differences in the Incidence and Clearance of Human Papilloma Virus (HPV): The HPV in Men (HIM) Study
Por:
Schabath M.B., Villa L.L., Lin, HY, Fulp W.J., Akogbe G.O., Abrahamsen M.E., Papenfuss M.R., Lazcano-Ponce E., Salmeron J., Quiterio M., Giuliano A.R.
Publicada:
1 oct 2013
Resumen:
Background: This analysis assessed the acquisition (incidence) and persistence (clearance) of human papilloma virus (HPV) infection by self-reported race among men in The HPV in Men (HIM) Study, a multinational prospective study of the natural history of genital HPV infections. Methods: Self-reported race was categorized as White, Black, Asian/Pacific Islander (PI), or multiple and mixed race. Genital samples were combined for HPV DNA testing and categorized by any, oncogenic, and non-oncogenic HPV infections. Results: Asian/PI race had significantly the lowest incidence of any, oncogenic, and non-oncogenic HPV infection (P < 0.001). In multivariable analyses, Asian/PI race was associated with a lower probability of acquiring any [HR = 0.63; 95% confidence interval (CI), 0.42-0.95] and non-oncogenic HPV infection (HR = 0.61; 95% CI, 0.40-0.93) when compared to Whites. No significant associations were evident for Asian/PI race for clearance. Multiple and mixed race was significantly ass
Filiaciones:
Schabath M.B.:
Department of Cancer Epidemiology and Center for Infection Research in Cancer (CIRC), United States
Department of Biostatistics, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive MRC, Tampa, FL 33612-9416, United States
Villa L.L.:
Ludwig Institute for Cancer Research, São Paulo, Brazil
Fulp W.J.:
Department of Biostatistics, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive MRC, Tampa, FL 33612-9416, United States
Akogbe G.O.:
Department of Cancer Epidemiology and Center for Infection Research in Cancer (CIRC), United States
Abrahamsen M.E.:
Department of Cancer Epidemiology and Center for Infection Research in Cancer (CIRC), United States
Papenfuss M.R.:
Department of Cancer Epidemiology and Center for Infection Research in Cancer (CIRC), United States
Lazcano-Ponce E.:
Instituto Nacional de Salud Pública, Mexico
Salmeron J.:
Instituto Nacional de Salud Pública, Mexico
Instituto Mexicano Del Segurio Social, Cuernavaca, Mexico
Quiterio M.:
Instituto Nacional de Salud Pública, Mexico
Giuliano A.R.:
Department of Cancer Epidemiology and Center for Infection Research in Cancer (CIRC), United States
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