Probable presence of an ubiquitous cryptic mitochondrial gene on the antisense strand of the cytochrome oxidase I gene
Por:
Faure E., Delaye L., Tribolo S., Levasseur A., Seligmann H., Barthelemy, RM
Publicada:
24 oct 2011
Resumen:
Background: Mitochondria mediate most of the energy production that occurs in the majority of eukaryotic organisms. These subcellular organelles contain a genome that differs from the nuclear genome and is referred to as mitochondrial DNA (mtDNA). Despite a disparity in gene content, all mtDNAs encode at least two components of the mitochondrial electron transport chain, including cytochrome c oxidase I (Cox1). Presentation of the hypothesis: A positionally conserved ORF has been found on the complementary strand of the cox1 genes of both eukaryotic mitochondria (protist, plant, fungal and animal) and alpha-proteobacteria. This putative gene has been named gau for (g) under bar ene (a) under bar ntisense (u) under bar biquitous in mtDNAs. The length of the deduced protein is approximately 100 amino acids. In vertebrates, several stop codons have been found in the mt gau region, and potentially functional gau regions have been found in nuclear genomes. However, a recent bioinformatics s
Filiaciones:
Faure E.:
LATP, CNRS-UMR 6632, IFR 48 Infectiopôle, Evolution biologique et modélisation, case 5, Université de Provence, Place Victor Hugo, 13331 Marseille cedex 3, France
Delaye L.:
Departamento de Ingeniería Genética, CINVESTAV, Irapuato Km 9.6 Libramiento Norte Carr. Irapuato-Leon, 36821 Irapuato Gto, Mexico
Tribolo S.:
Biovays SAS, Université de Provence, 3, place Victor Hugo, 13331 Marseille cedex 3, France
Levasseur A.:
INRA, UMR1163 de Biotechnologie des Champignons Filamenteux, IFR86-BAIM, Aix-Marseille Universités, ESIL, 163 avenue de Luminy, CP 925, 13288 Marseille Cedex 09, France
Aix-Marseille Univ, UMR1163 BCF, 163 avenue de Luminy, CP925, 13288 Marseille Cedex 09, France
Seligmann H.:
National Collections of Natural History, The Hebrew University of Jerusalem, 91904 Jerusalem, Israel
Department of Life Sciences, Ben Gurion University, 84105 Beer Sheva, Israel
Gold
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