Base-free two-step synthesis of 1,3-diketones and beta-ketoesters from alpha-diazocarbonyl compounds, trialkylboranes, and aromatic aldehydes
Por:
Sanchez-Carmona, MA, Contreras-Cruz, DA, Miranda, LD
Publicada:
1 ene 2011
Resumen:
We describe a convergent, base-free two-step synthesis of 1,3-diketones and beta-ketoesters from alpha-diazocarbonyl compounds, trialkylboranes, and aromatic aldehydes in a three-component process. The synthetic potential of this protocol was underscored by the synthesis of several symmetrical 1,3,5-triaryl-4-alkyl and 1,3,4,5-tetraryl substituted pyrazoles in a three-step sequence.
Filiaciones:
Sanchez-Carmona, MA:
Univ Nacl Autonoma Mexico, Coyoacan 04510, DF, Mexico
Contreras-Cruz, DA:
Univ Nacl Autonoma Mexico, Coyoacan 04510, DF, Mexico
Miranda, LD:
Univ Nacl Autonoma Mexico, Coyoacan 04510, DF, Mexico
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