Chronic Toxicity, Genotoxic Assay, and Phytochemical Analysis of Four Traditional Medicinal Plants
Por:
Sortibran, AC, Tellez, MGO, Ocotero, VM, Carballo-Ontiveros, MA, Garcia, AM, Valdes, RJJ, Gutierrez, ER, Rodriguez-Arnaiz, R
Publicada:
1 sep 2011
Resumen:
Four medicinal plants-Tecoma stans, Ligusticum porteri, Monarda austromontana, and Poliomintha longiflora, which are distributed in tropical and subtropical countries of the American continent-are widely used in folk medicine to treat diseases such as diarrhea and dysentery. In addition, T. stans and P. longiflora are extensively used as hypoglycemic agents, and M. austromontana and P. longiflora are used as condiments. The plants were collected, identified, dried, and pulverized. Solvent extraction was prepared by maceration of the plant samples, and the phytochemical composition of the extracts was determined by using standard analysis procedures. Phytochemical analysis showed the presence of triterpenoids/steroids, flavonoids, and phenols/tannins and, in L. porteri, traces of alkaloids. After the elimination of solvents in vacuo, the extracts were administrated to Drosophila larvae to test their toxicity and genotoxicity. Third instar larvae were chronically fed with the phytoextrac
Filiaciones:
Sortibran, AC:
Univ Nacl Autonoma Mexico, Fac Sci, Dept Cellular Biol, Genet Lab, Mexico City 04510, DF, Mexico
Tellez, MGO:
Univ Nacl Autonoma Mexico, Fac Sci, Dept Cellular Biol, Genet Lab, Mexico City 04510, DF, Mexico
Ocotero, VM:
Univ Nacl Autonoma Mexico, Fac Ciencias, Dept Ecol & Nat Resources, Lab Phytochem, Mexico City 04510, DF, Mexico
Carballo-Ontiveros, MA:
Univ Nacl Autonoma Mexico, Fac Sci, Dept Cellular Biol, Genet Lab, Mexico City 04510, DF, Mexico
Garcia, AM:
Univ Nacl Autonoma Mexico, Fac Sci, Dept Cellular Biol, Genet Lab, Mexico City 04510, DF, Mexico
Valdes, RJJ:
Univ Nacl Autonoma Mexico, Fac Sci, Dept Cellular Biol, Genet Lab, Mexico City 04510, DF, Mexico
Gutierrez, ER:
Univ Nacl Autonoma Mexico, Fac Sci, Dept Cellular Biol, Genet Lab, Mexico City 04510, DF, Mexico
Rodriguez-Arnaiz, R:
Univ Nacl Autonoma Mexico, Fac Sci, Dept Cellular Biol, Genet Lab, Mexico City 04510, DF, Mexico
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