Effect of temperature on triazole and bistriazole formation through copper-catalyzed alkyne-azide cycloaddition
Por:
Gonzalez, J, Perez, VM, Jimenez, DO, Lopez-Valdez, G, Corona, D, Cuevas-Yanez, E
Publicada:
6 jul 2011
Resumen:
Temperature is an important factor in the copper catalyzed alkyne azide cycloaddition under oxidative conditions. 1,2,3-Triazoles were obtained in high yields when several alkynes and azides were reacted at methanol reflux using catalytic amounts of both copper iodide and sodium hydroxide. On the other hand, bistriazoles were major products when reactions were performed at -35 degrees C using excess sodium hydroxide. (C) 2011 Elsevier Ltd. All rights reserved.
Filiaciones:
Gonzalez, J:
Ctr Conjunto Invest Quim Sustentable UAEM UNAM, Toluca 52000, Estado Mexico, Mexico
Perez, VM:
Ctr Conjunto Invest Quim Sustentable UAEM UNAM, Toluca 52000, Estado Mexico, Mexico
Jimenez, DO:
Ctr Conjunto Invest Quim Sustentable UAEM UNAM, Toluca 52000, Estado Mexico, Mexico
Lopez-Valdez, G:
Ctr Conjunto Invest Quim Sustentable UAEM UNAM, Toluca 52000, Estado Mexico, Mexico
Corona, D:
Ctr Conjunto Invest Quim Sustentable UAEM UNAM, Toluca 52000, Estado Mexico, Mexico
Cuevas-Yanez, E:
Ctr Conjunto Invest Quim Sustentable UAEM UNAM, Toluca 52000, Estado Mexico, Mexico
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