Effect of Rotavirus Vaccination on Death from Childhood Diarrhea in Mexico
Por:
Richardson V., Hernandez-Pichardo J., Quintanar-Solares M., Esparza-Aguilar M., Johnson B., Gomez-Altamirano C.M., Parashar U., Patel M.
Publicada:
28 ene 2010
Categoría:
Medicine (miscellaneous)
Resumen:
BACKGROUND A phased introduction of a monovalent rotavirus vaccine occurred in Mexico from February 2006 through May 2007. We assessed the effect of vaccination on deaths from diarrhea in Mexican children in 2008 and 2009. METHODS We obtained data on deaths from diarrhea, regardless of cause, from January 2003 through May 2009 in Mexican children under 5 years of age. We compared diarrhea-related mortality in 2008 and during the 2008 and 2009 rotavirus seasons with the mortality at baseline (2003-2006), before the introduction of the rotavirus vaccine. Vaccine coverage was estimated from administrative data. RESULTS By December 2007, an estimated 74% of children who were 11 months of age or younger had received one dose of rotavirus vaccine. In 2008, there were 1118 diarrhea-related deaths among children younger than 5 years of age, a reduction of 675 from the annual median of 1793 deaths during the 2003-2006 period. Diarrhea-related mortality fell from an annual median of 18.1 deaths
Filiaciones:
Richardson V.:
National Center for Child and Adolescent Health, Ministry of Health, Mexico City, Mexico
Hernandez-Pichardo J.:
National Center for Child and Adolescent Health, Ministry of Health, Mexico City, Mexico
Quintanar-Solares M.:
National Center for Child and Adolescent Health, Ministry of Health, Mexico City, Mexico
Esparza-Aguilar M.:
National Center for Child and Adolescent Health, Ministry of Health, Mexico City, Mexico
Johnson B.:
National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States
Gomez-Altamirano C.M.:
National Center for Child and Adolescent Health, Ministry of Health, Mexico City, Mexico
Parashar U.:
National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States
Patel M.:
National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States
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