Spatial memory: Theoretical basis and comparative review on experimental methods in rodents


Por: Paul, CM, Magda G., Abel S.

Publicada: 5 nov 2009
Categoría: Behavioral Neuroscience

Resumen:
The assessment of learning and memory in animal models has been widely employed in scientific research for a long time. Among these models, those representing diseases with primary processes of affected memory - such as amnesia, dementia, brain aging, etc. - studies dealing with the toxic effects of specific drugs, and other exploring neurodevelopment, trauma, epilepsy and neuropsychiatric disorders, are often called on to employ these tools. There is a diversity of experimental methods assessing animal learning and memory skills. Overall, mazes are the devices mostly used today to test memory in rodents; there are several types of them, but their real usefulness, advantages and applications remain to be fully established and depend on the particular variant selected by the experimenter. The aims of the present article are first, to briefly review the accumulated knowledge in regard to spatial memory tasks; second, to bring the reader information on the different types of rodent mazes

Filiaciones:
Magda G.:
 Laboratorio de Plasticidad, Departmento de Neurobiología Conductual y Cognitiva, Instituto de Neurobiología, Mexico

Abel S.:
 Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, 14269, Mexico
ISSN: 01664328
Editorial
ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, Países Bajos
Tipo de documento: Review
Volumen: 203 Número: 2
Páginas: 151-164
WOS Id: 000268364100001
ID de PubMed: 19467271

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