Impact on Erectile Function and Sexual Quality of Life of Couples: A Double-Blind, Randomized, Placebo-Controlled Trial of Tadalafil Taken Once Daily
Por:
Rubio-Aurioles E., Kim E.D., Rosen R.C., Porst H., Burns P., Zeigler H., Wong D.G.
Publicada:
1 may 2009
Resumen:
Clinical research on erectile dysfunction (ED) has focused primarily on the male and the impact of treatment on their erectile function (EF) and sexual quality of life. However, ED affects the quality of life of both the male and the female partner. The literature examining the impact on the female partner resulting from treating the male's ED is somewhat limited. To determine the efficacy of tadalafil 5 mg taken once daily compared with placebo on men's EF and sexual quality of life, and to determine the impact of this treatment on the female partner's sexual quality of life. The co-primary outcome measures for this study were changes from baseline to end point in the EF domain of the International Index of Erectile Function (IIEF), the Sexual Encounter Profile (SEP) question 2 (SEP-2) and question 3 (SEP-3), and the Sexual Quality of Life (SQoL) domain of the Sexual Life Quality Questionnaire (SLQQ) (subject and partner). Following a 4-week treatment-free run-in phase, 342 subjects a
Filiaciones:
Rubio-Aurioles E.:
Asociación Mexicana para la Salud Sexual, A.C. (AMSSAC) - Sexual Medicine Research, Mexico City 14000, Mexico
Kim E.D.:
University of Tennessee Graduate School of Medicine, Knoxville, TN, United States
Rosen R.C.:
New England Research Institutes, Watertown, MA, United States
Porst H.:
Lilly USA, LLC, Indianapolis, IN, United States
Burns P.:
Private Practice, Hamburg, Germany
Zeigler H.:
Private Practice, Hamburg, Germany
Wong D.G.:
Private Practice, Hamburg, Germany
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