Hormonal and metabolic rhythms associated with the daily scheduled nursing in rabbit pups
Por:
Morgado E., Gordon M.K., Minana-Solis, MD, Meza E., Levine S., Escobar C., Caba M.
Publicada:
1 ago 2008
Resumen:
Young rabbits are nursed every 24 h for a period of 3-5 min. As a consequence, pups are synchronized to this nursing event; this synchronization is characterized by increased locomotor activity and a peaking of core temperature and plasma corticosterone in anticipation of the daily meal. Ghrelin is a hormone suggested to play a role in meal initiation and to promote food intake. The present study explored the role of ghrelin in food-entrained conditions. Newborn rabbits were maintained in constant darkness and nursed once daily at 1000 by the lactating dam. On postnatal day 7, rabbits were killed at six different time points to complete a 24-h cycle. All pups developed locomotor rhythms entrained by mealtime and exhibited anticipatory activity. Food-entrained rhythms in plasma corticosterone and free fatty acids were observed even if two meals were omitted. In contrast, daily food-driven rhythms in stomach weight, plasma glucose, liver glycogen, and ghrelin did not persist when two mea
Filiaciones:
Morgado E.:
Laboratorio de Biología de la Reproducción, IIB, Universidad Veracruzana, Xalapa, Veracruz, Mexico
Gordon M.K.:
Department of Psychology, University of Delaware, Newark, DE, United States
Minana-Solis, MD:
Univ Nacl Autonoma Mexico, Fac Med, Dept Anat, Mexico City 04510, DF, Mexico
Meza E.:
Laboratorio de Biología de la Reproducción, IIB, Universidad Veracruzana, Xalapa, Veracruz, Mexico
Levine S.:
Center for Neurosciences, University of California, Davis, CA, United States
Escobar C.:
Univ Nacl Autonoma Mexico, Fac Med, Dept Anat, Mexico City 04510, DF, Mexico
Caba M.:
Laboratorio de Biología de la Reproducción, IIB, Universidad Veracruzana, Xalapa, Veracruz, Mexico
Lab. Biol. de la Reproducción, IIB, Universidad Veracruzana, AP 114, Xalapa 91000, Ver., Mexico
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