Waking EEG signs of non-restoring sleep in primary insomnia patients
Por:
Corsi-Cabrera M., Rojas-Ramos O.A., del Río-Portilla Y.
Publicada:
1 mar 2016
Resumen:
Objective: Subjective feelings of insufficient and non-restorative sleep
are core symptoms of primary insomnia. Sleep has a restorative effect on
next-day waking EEG activity, whereas sleep loss has non-restorative
effects in good sleepers. We proposed to explore waking EEG activity in
primary insomniacs the evening before, and the morning after, a night of
sleep, in order to detect signs of morning hyperarousal and
non-restoring sleep that might explain the subjective feelings despite
the absence of objective signs in polysomnography.
Method: Pre-sleep (10 pm) and post-sleep (10 am) waking EEG activity was
analyzed in 10 non-medicated primary insomniacs and matched control
subjects. Beta and Gamma absolute power and EEG temporal coupling were
obtained. Participants also evaluated subjective sleep quantity and
quality.
Results: Insomnia patients evaluated their sleep as non-restorative and
insufficient. Compared to presleep, during post-sleep control subjects
exhibited significantly decreased Beta and Gamma power and reduced
synchronization among anterior and posterior regions, consistent with
restoring effects of sleep. Insomnia patients showed no beneficial
effects of sleep on these EEG parameters.
Conclusion: Insomniacs are hyper-aroused during morning wakefulness and
they do not benefit from preceding sleep.
Significance: Our study adds new knowledge to our understanding of the
physiopathology of insomnia. (c) 2015 International Federation of
Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights
reserved.
Filiaciones:
Corsi-Cabrera M.:
Univ Nacl Autonoma Mexico, Fac Psicol, Sleep Lab, Ave Univ 3004, Mexico City 04510, DF, Mexico
Sleep Laboratory, Facultad de Psicología, Universidad Nacional Autónoma de México, Av. Universidad 3004, D.F., México, 04510, Mexico
Rojas-Ramos O.A.:
Univ Nacl Autonoma Mexico, Fac Psicol, Sleep Lab, Ave Univ 3004, Mexico City 04510, DF, Mexico
Univ Nacl Autonoma Mexico, Fac Psicol, Dept Psychophysiol, Ave Univ 3004, Mexico City 04510, DF, Mexico
Sleep Laboratory, Facultad de Psicología, Universidad Nacional Autónoma de México, Av. Universidad 3004, D.F., México, 04510, Mexico
Departament of Psychophysiology, Facultad de Psicología, Universidad Nacional Autónoma de México, Av. Universidad 3004, D.F., México, 04510, Mexico
del Río-Portilla Y.:
Univ Nacl Autonoma Mexico, Fac Psicol, Sleep Lab, Ave Univ 3004, Mexico City 04510, DF, Mexico
Univ Nacl Autonoma Mexico, Fac Psicol, Dept Psychophysiol, Ave Univ 3004, Mexico City 04510, DF, Mexico
Sleep Laboratory, Facultad de Psicología, Universidad Nacional Autónoma de México, Av. Universidad 3004, D.F., México, 04510, Mexico
Departament of Psychophysiology, Facultad de Psicología, Universidad Nacional Autónoma de México, Av. Universidad 3004, D.F., México, 04510, Mexico
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