Anatomic and functional properties of bulboglandularis striated muscle support its contribution as sphincter in female rabbit micturition
Por:
Corona-Quintanilla D.L., López-Juárez R., Zempoalteca R., Cuevas E., Castelán F., Martínez-Gómez M.
Publicada:
1 ago 2016
Resumen:
PurposeTo determine anatomic and functional properties of the
bulboglandularis muscle (Bgm) for clarifying its role in micturition in
female rabbits.
Material and MethodsVirgin female rabbits were used to describe the
gross anatomy and innervation of the Bgm, to determine the effect of the
Bgm contraction on urethral pressure, and to evaluate the Bgm activity
during the induced-micturition. Both electromyogram and cystometrogram
activity were simultaneously recorded in urethane-anesthetized rabbits.
Bladder function was assessed measuring standard urodynamic variables
before and after blocking the Bgm activity for approaching its
contribution to micturition. The relevance of the Bgm activation for
micturition was approached applying lidocaine injections.
ResultsThe Bgm was composed of circularly oriented striated fibers
enveloping distal urethra and pelvic vagina. Both the venous plexus and
urethra were comprised by the Bgm contraction induced by electrical
stimulation. The Bgm showed bursts of tonic activity at the storage
phase of micturition that gradually decreased until turning off as the
onset of the voiding phase. The voided volume, the voiding efficiency,
the threshold pressure, and the maximal pressure were decreased after
lidocaine injection. Contrastingly, the threshold volume, the residual
volume, the voiding duration, and the urethral resistance at voiding
were increased.
ConclusionsPresent anatomical and physiological findings support that
the Bgm acts as a sphincter during micturition of female rabbits.
Neurourol. Urodynam. 35:689-695, 2016. (c) 2015 Wiley Periodicals, Inc.
Filiaciones:
Corona-Quintanilla D.L.:
Centro Tlaxcala de Biología de la Conducta, Universidad Autónoma de Tlaxcala (UATx), Tlaxcala, Mexico
López-Juárez R.:
Doctorado en Ciencias Biológicas, Universidad Autónoma de Tlaxcala, Tlaxcala, Mexico
Zempoalteca R.:
Centro Tlaxcala de Biología de la Conducta, Universidad Autónoma de Tlaxcala (UATx), Tlaxcala, Mexico
Cuevas E.:
Centro Tlaxcala de Biología de la Conducta, Universidad Autónoma de Tlaxcala (UATx), Tlaxcala, Mexico
Castelán F.:
Centro Tlaxcala de Biología de la Conducta, Universidad Autónoma de Tlaxcala (UATx), Tlaxcala, Mexico
Martínez-Gómez M.:
Centro Tlaxcala de Biología de la Conducta, Universidad Autónoma de Tlaxcala (UATx), Tlaxcala, Mexico
Departamento de Biología Celular y Fisiología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), México D.F., Mexico
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