Effect of crude extracts of Erythrina americana Mill. on aggressive behavior in rats
Por:
Garín-Aguilar M.E., Ramírez Luna J.E., Soto-Hernández M., Valencia del Toro G., Martínez Vázquez M.
Publicada:
1 ene 2000
Resumen:
Three alkaloid fractions were obtained from seeds of Erythrina americana: free alkaloids in hexane, free alkaloids in methanol and liberated alkaloids. The pharmacological evaluation of these fractions on rats showed that, administered in a dose of 3 mg/kg, the three fractions diminished the aggressive behavior. This is comparable when diazepam is used as a control. An interaction between the cholinergic and GABAergic system could be suggested. Copyright (C) 2000 Elsevier Science Ireland Ltd.
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